When you have 'Only buy when there are positive pairs' enabled, the trading bot will only place orders if there has been a positive change percentage in the last X hours or minutes for at least one of your selected currencies. If there is no positive change in one of your chosen currencies during the period you can configure in the following setting, your trading bot will not place new orders based on your trading strategy or trading signals.
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The trading bot will always place new orders when using TradingView Alerts or manual orders.